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April 6, 2005JAMA632 citations

Efficacy and Tolerability of Long-Acting Injectable Naltrexone for Alcohol Dependence

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JGJames C. GarbuttUniversity of North Carolina at Chapel Hill
Henry R. Kranzler
Henry R. KranzlerBoston University
SOStephanie S. O’MalleyEmory University

Key Points

  • The aim is to evaluate the efficacy and tolerability of long-acting injectable naltrexone in treating alcohol dependence.
  • Long-acting naltrexone was administered to alcohol-dependent patients.
  • Participants were treatment-seeking individuals during a 6 months therapy period.
  • Patients experienced significant reductions in heavy drinking during the treatment period.
  • Long-acting naltrexone was well tolerated by the patients.

Abstract

Long-acting naltrexone was well tolerated and resulted in reductions in heavy drinking among treatment-seeking alcohol-dependent patients during 6 months of therapy. These data indicate that long-acting naltrexone can be of benefit in the treatment of alcohol dependence.

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Cite This Study

Garbutt et al. (2005) studied this question.

synapsesocial.com/papers/69d8927e8c03fbaff8bef6fdhttps://doi.org/10.1001/jama.293.13.1617
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