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April 10, 2026Anesthesia & Analgesia0 citations

Effect of Local Anesthetic Solution at Different Temperatures for Epidural Labor Analgesia on Intrapartum Fever: A Randomized Clinical Trial

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HWHai-Chao WeiNantong UniversityYCYu CaoUniversity of Nottingham Ningbo ChinaXWXiaoyang WuNantong University

Key Points

  • The aim is to assess the effect of local anesthetic temperatures on the incidence of intrapartum fever during labor.
  • Conducted a randomized clinical trial with participants receiving epidural analgesia.
  • Compared warmed local anesthetics (37°C) to standard temperature solutions.
  • Monitored temperature changes during labor.
  • Achieved a 50% reduction in the incidence of fever with warmed anesthetics.
  • Reduction did not meet the predefined threshold of 60%.

Abstract

Although we found a 50% reduction in the incidence of temperature rise using warmed (37°C) local anesthetics for epidural labor analgesia, this did not reach our preset threshold of 60% reduction.

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Cite This Study

Wei et al. (2026) studied this question.

synapsesocial.com/papers/69d893eb6c1944d70ce04f22https://doi.org/10.1213/ane.0000000000008041
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