Lumbar spinal stenosis (LSS) is a prevalent degenerative spinal disorder among older adults and represents the most common indication for spinal surgery in this population. Although surgical treatment is definitive for refractory cases, conservative management remains the cornerstone of initial treatment, with pharmacotherapy playing a central role. However, pharmacological strategies for LSS are largely symptomatic and are frequently complicated by polypharmacy and medication-related adverse events in older adults.
Fujita et al. (2026) studied this question.