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April 10, 2026Acta Obstetricia Et Gynecologica Scandinavica0 citationsOpen Access

Understanding the consequences of being RhD immunized during pregnancy 10 years after introduction of targeted routine antenatal anti‐D prophylaxis: A retrospective nationwide cohort study

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APAnna ParhamaaUniversity of HelsinkiRJRiina JernmanUniversity of HelsinkiMGMika GisslerKarolinska Institutet

Key Points

  • This research investigates the long-term effects of RhD immunization during pregnancy following the implementation of targeted anti-D prophylaxis.
  • Conducted a retrospective nationwide cohort analysis
  • Evaluated changes in the prevalence of anti-D immunizations over ten years
  • Assessed screening strategies and neonatal care pathways
  • Anti-D immunizations reduced by more than half over the decade
  • Declining birth rates contributed to lower overall case numbers
  • A significant portion of pregnancies still requires close monitoring and intervention

Abstract

Ten years after the introduction of targeted RAADP, the prevalence of anti-D immunizations was reduced by more than half. Declining birth rates further reduce overall case numbers but do not lessen the complexity of care needed. A significant proportion of anti-D pregnancies still require close monitoring or intervention. Optimizing screening strategies, referral pathways, and readiness for neonatal treatment remains essential in the evolving landscape of HDFN prevention and management.

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Cite This Study

Parhamaa et al. (2026) studied this question.

synapsesocial.com/papers/69d895ea6c1944d70ce0717ahttps://doi.org/10.1111/aogs.70195
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