Advanced Regenerative Drainage and Immunomodulatory Protocol for Dermal Filler–Induced Skin Necrosis: A Prospective Clinical Case Series | Synapse
April 10, 2026Open Access
Advanced Regenerative Drainage and Immunomodulatory Protocol for Dermal Filler–Induced Skin Necrosis: A Prospective Clinical Case Series
Key Points
The aim is to evaluate the effectiveness and safety of the Advanced Regenerative Drainage and Immunomodulatory Protocol (ARDIP) for treating dermal filler-induced skin necrosis.
ARDIP demonstrated a safe application in clinical settings
Significant reduction in necrosis symptoms observed
Effective in restoring skin integrity in affected areas
Abstract
ARDIP appears to be a safe and effective multimodal strategy for the management of filler-induced skin necrosis, addressing both mechanical vascular obstruction and the associated inflammatory cascade.