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April 10, 2026Therapeutic Apheresis and Dialysis0 citations

Risk Factors for Bleeding and Thromboembolic Events in Patients With Chronic Kidney Disease on Maintenance Hemodialysis: A Retrospective Case‐Control Study Based on the Roxadustat User Population

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RMRuijie ManYLYufeng LiYZYue Zhang

Key Points

  • This research aims to identify risk factors for bleeding and thromboembolic events in CKD patients undergoing hemodialysis, particularly focusing on roxadustat usage.
  • Conducted a retrospective case-control study.
  • Analyzed data from the roxadustat user population.
  • Evaluated the incidence of bleeding and thromboembolic events.
  • Roxadustat use was linked to a lower risk of both bleeding and thromboembolic events.
  • Stabilization of hemoglobin levels was observed in patients on roxadustat.
  • Improved iron metabolism and reduced inflammation were noted as possible mediating factors.

Abstract

Roxadustat use was associated with a lower risk of bleeding and thromboembolic events in CKD patients on hemodialysis. This association may be mediated through the stabilization of hemoglobin levels, modulation of iron metabolism, and attenuation of inflammation.

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Cite This Study

Man et al. (2026) studied this question.

synapsesocial.com/papers/69d896166c1944d70ce07560https://doi.org/10.1002/1744-9987.70139
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