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April 10, 2026Therapeutic Delivery

Dual-action depot formulation of hyaluronic acid/poloxamer in-situ gel enclosing lavender oil-based syringic acid nanoemulsion for enhanced intra-articular treatment of osteoarthritis

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Authors

NANoor AssalemHAHend Abd-AllahEEEnas Elmowafy

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Overview

Innovative formulation enhances therapeutic efficacy in intra-articular osteoarthritis treatment, indicating its potential benefits.

Key Points

  • The research aims to evaluate a new formulation combining hyaluronic acid and lavender oil for treating osteoarthritis.
  • Developed a dual-action depot formulation using HA, poloxamer, and lavender oil.
  • Enclosed syringic acid nanoemulsion within the in-situ gel.
  • Assessed therapeutic efficacy for intra-articular applications.
  • The nanoemulsion displayed enhanced sustained therapeutic effects.
  • Indicated potential for improved intra-articular delivery and treatment of osteoarthritis.

Cite This Study

Assalem et al. (2026) studied this question.

synapsesocial.com/papers/69d896406c1944d70ce07902https://doi.org/10.1080/20415990.2026.2653442
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