July 14, 2012Cancer Discovery199 citations

BRAF L597 Mutations in Melanoma Are Associated with Sensitivity to MEK Inhibitors

KDKimberly B. Dahlman JXJunfeng Xia KHKatherine E. Hutchinson

Key Points

Key points are not available for this paper at this time.

Abstract

This study shows that cells harboring BRAF(L597R) mutants are sensitive to MEK inhibitor treatment, providing a rationale for routine screening and therapy of BRAF(L597R)-mutant melanoma.

Ask AI

Helpful

Bookmark

View Full Paper

Cite This Study

Dahlman et al. (2012) studied this question.

synapsesocial.com/papers/69d89ba3183921ebcaae2d49 https://doi.org/10.1158/2159-8290.cd-12-0097

Ask AI

Helpful

Bookmark

View Full Paper

July 14, 2012Cancer Discovery199 citations

BRAF L597 Mutations in Melanoma Are Associated with Sensitivity to MEK Inhibitors

View Full Paper

KDKimberly B. Dahlman JXJunfeng Xia KHKatherine E. Hutchinson

Key Points

Key points are not available for this paper at this time.

Abstract

This study shows that cells harboring BRAF(L597R) mutants are sensitive to MEK inhibitor treatment, providing a rationale for routine screening and therapy of BRAF(L597R)-mutant melanoma.

Ask AI

Helpful

Bookmark

View Full Paper

Cite This Study

Dahlman et al. (2012) studied this question.

synapsesocial.com/papers/69d89ba3183921ebcaae2d49 https://doi.org/10.1158/2159-8290.cd-12-0097

Ask AI

Helpful

Bookmark

View Full Paper