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June 16, 2021Journal of Advanced Research232 citationsOpen Access

Skin cancer biology and barriers to treatment: Recent applications of polymeric micro/nanostructures

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NKNazeer Hussain KhanMMMaria MirLQLei Qian

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Abstract

In this review, we explained new understandings about onset and development of skin cancer and described its management via polymeric micro/nano carriers-based therapies, highlighting the current key bottlenecks and future prospective in this field. In therapeutic drug/gene delivery approaches, polymeric carriers-based system is the most promising strategy. This review discusses that how polymers have successfully been exploited for development of micro/nanosized systems for efficient delivery of anticancer genes and drugs overcoming all the barriers and limitations associated with available conventional therapies. In addition to drug/gene delivery, intelligent polymeric nanocarriers platforms have also been established for combination anticancer therapies including photodynamic and photothermal, and for theranostic applications. This portfolio of latest approaches could promote the blooming growth of research and their clinical availability.

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Khan et al. (2021) studied this question.

synapsesocial.com/papers/69d8a38da5ecc596b5d18088https://doi.org/10.1016/j.jare.2021.06.014
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