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December 6, 2015New England Journal of Medicine1,594 citationsOpen Access

Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia

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JBJan A. BurgerATAlessandra TedeschiPBPaul M. Barr

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Abstract

Ibrutinib was superior to chlorambucil in previously untreated patients with CLL or small lymphocytic lymphoma, as assessed by progression-free survival, overall survival, response rate, and improvement in hematologic variables. (Funded by Pharmacyclics and others; RESONATE-2 ClinicalTrials.gov number, NCT01722487.).

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Burger et al. (2015) studied this question.

synapsesocial.com/papers/69d8cc7ad2f7327e70ae44f7https://doi.org/10.1056/nejmoa1509388
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Also Consider

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