PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 18, 2015New England Journal of Medicine2,871 citationsOpen Access

Driving Pressure and Survival in the Acute Respiratory Distress Syndrome

View Full Paper
MAMarcelo B. P. AmatoMMMaureen O. MeadeASArthur S. Slutsky

Key Points

  • This research aims to determine the relationship between driving pressure and survival in acute respiratory distress syndrome.
  • Evaluation of ventilator settings and their impact on driving pressure.
  • Analysis of survival rates in association with changes in driving pressure.
  • Data collection from various support agencies.
  • Decreases in driving pressure led to significantly increased survival rates.
  • ΔP was identified as the best indicator of risk stratification regarding survival.

Abstract

We found that ΔP was the ventilation variable that best stratified risk. Decreases in ΔP owing to changes in ventilator settings were strongly associated with increased survival. (Funded by Fundação de Amparo e Pesquisa do Estado de São Paulo and others.).

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Amato et al. (2015) studied this question.

synapsesocial.com/papers/69d8d75d33ca018b39ae42a3https://doi.org/10.1056/nejmsa1410639
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures. Protection by positive end-expiratory pressure.1974 · 948 citations
  2. 2Acute Respiratory Distress Syndrome2012 · 8,913 citations
  3. 3Deformation-Induced Injury of Alveolar Epithelial Cells2000 · 344 citations
  4. 4Evaluation of a Ventilation Strategy to Prevent Barotrauma in Patients at High Risk for Acute Respiratory Distress Syndrome1999 · 309 citations
  5. 5Advances in Social Science Research Using R2009 · 91 citations