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September 8, 2014New England Journal of Medicine1,669 citations

Oral Glucocorticoid-Sparing Effect of Mepolizumab in Eosinophilic Asthma

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EBElisabeth H. BelSWSally E. WenzelPTPhilip J. Thompson

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Abstract

In patients requiring daily oral glucocorticoid therapy to maintain asthma control, mepolizumab had a significant glucocorticoid-sparing effect, reduced exacerbations, and improved control of asthma symptoms. (Funded by GlaxoSmithKline; SIRIUS ClinicalTrials.gov number, NCT01691508.).

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Bel et al. (2014) studied this question.

synapsesocial.com/papers/69d92360da3af5b1d0835c52https://doi.org/10.1056/nejmoa1403291
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