Are the Systemic Immune Inflammation Index (SII) and System Inflammation Response Index (SIRI) associated with the risk of all-cause and cardiovascular mortality in US adults?
Elevated systemic inflammation indices (SII and SIRI) are associated with an increased long-term risk of all-cause and cardiovascular mortality in US adults.
Two novel inflammatory composite indices, SII and SIRI, were closely associated with cardiovascular death and all-cause death, and more attention should be paid to systemic inflammation to provide better preventive strategies.
Xia et al. (2023) studied this question.