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September 7, 2022Hypertension134 citationsOpen Access

High HDL (High-Density Lipoprotein) Cholesterol Increases Cardiovascular Risk in Hypertensive Patients

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VTValentina TrimarcoRIRaffaele IzzoCMCarmine Morisco

Structured PICO

Is there an association between HDL-C levels and the risk of cardiovascular events in male patients with hypertension?

P
Population
Male patients with hypertension
I
Intervention
HDL-C levels (specifically high HDL-C)
O
Outcome
Cardiovascular eventshard clinical

A U-shaped association exists between HDL-C levels and cardiovascular events in hypertensive men, suggesting that high HDL-C may paradoxically increase cardiovascular risk.

Abstract

Our data demonstrate that there is a U-shaped association between HDL-C and the risk of cardiovascular events in male patients with hypertension.

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Cite This Study

Trimarco et al. (2022) studied this question.

synapsesocial.com/papers/69d9473e16f0d2beeba3c472https://doi.org/10.1161/hypertensionaha.122.19912
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