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June 1, 2004Clinical Cancer Research810 citations

Phase I and Pharmacokinetic Study of Genexol-PM, a Cremophor-Free, Polymeric Micelle-Formulated Paclitaxel, in Patients with Advanced Malignancies

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TKTae‐You KimDKDong-Wan KimJCJae‐Yong Chung

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Abstract

The main dose-limiting toxicities were neuropathy, myalgia, and neutropenia, and the recommended dosage for a phase II study is 300 mg/m(2). Genexol-PM is believed to be superior to conventional paclitaxel in terms of the obviation of premedication and the delivery of higher paclitaxel doses without additional toxicity.

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Kim et al. (2004) studied this question.

synapsesocial.com/papers/69d962635e5bcb4e3b835f87https://doi.org/10.1158/1078-0432.ccr-03-0655
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