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This article investigates by means of US Patent and Trademark Office (USPTO) patent data whether technological relatedness at the city level was a crucial driving force behind technological change in 366 US cities from 1981 to 2010. Based on a three-way fixed-effects model, we find that the entry probability of a new technology in a city increases by 30% if the level of relatedness with existing technologies in the city increases by 10%, while the exit probability of an existing technology decreases by 8%.
Boschma et al. (2014) studied this question.