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Synapse
May 15, 2023Antibiotics37 citationsOpen Access

Six Long-Standing Questions about Antibiotic Prophylaxis in Surgery

MSMassimo SartelliMBMarja A. BoermeesterMCMiguel Caínzos

Structured PICO

P
Population
Surgical patients
I
Intervention
Surgical antibiotic prophylaxis (SAP)
O
Outcome
Prevention of surgical site infections (SSIs)

This expert panel document provides guiding principles for the appropriate administration of surgical antibiotic prophylaxis to prevent surgical site infections.

Abstract

Surgical site infections (SSIs) are the most common adverse event occurring in surgical patients. Optimal prevention of SSIs requires the bundled integration of a variety of measures before, during, and after surgery. Surgical antibiotic prophylaxis (SAP) is an effective measure for preventing SSIs. It aims to counteract the inevitable introduction of bacteria that colonize skin or mucosa into the surgical site during the intervention. This document aims to guide surgeons in appropriate administration of SAP by addressing six key questions. The expert panel identifies a list of principles in response to these questions that every surgeon around the world should always respect in administering SAP.

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Cite This Study

Sartelli et al. (2023) studied this question.

synapsesocial.com/papers/69d97e901ad561c6736846eahttps://doi.org/10.3390/antibiotics12050908
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antibiotic prescribing practices in general surgery: a mixed methods quality improvement project2021 · 14 citations
  2. 2Ertapenem Concentrations in Obese Patients Undergoing Surgery2022 · 5 citations
  3. 3Antibiotic Prophylaxis in Patients Undergoing Open Mesh Repair of Inguinal Hernia: A Meta-Analysis2012 · 47 citations
  4. 4Timeliness and use of antibiotic prophylaxis in selected inpatient surgical procedures1996 · 132 citations
  5. 5Access to effective antimicrobials: a worldwide challenge2015 · 1,494 citations