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November 1, 2021Acta Anaesthesiologica ScandinavicaOpen Access

Total opioid‐free general anaesthesia can improve postoperative outcomes after surgery, without evidence of adverse effects on patient safety and pain management: A systematic review and meta‐analysis

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Why the study?

There is a need for more evidence-based non-opioid anaesthetic protocols across different surgical settings and postoperative phases.

Does total opioid-free general anaesthesia improve postoperative outcomes in patients undergoing surgery?

Design

Systematic review and meta-analysis

Authors

AOAlexander OlaussonCSCarl Johan SvenssonPAPaulin Andréll

Discussion

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Overview

Opioid-free anaesthesia merits consideration in perioperative protocols; confirms and extends RCT evidence on recovery without safety trade-offs.

Structured PICO

Does total opioid-free general anaesthesia improve postoperative outcomes in patients undergoing surgery?

P
Population
Patients in several surgical settings
I
Intervention
Total opioid-free general anaesthesia
O
Outcome
Postoperative outcomes, patient safety, and pain managementsafety

Total opioid-free general anaesthesia may improve postoperative outcomes without adverse effects on safety or pain management.

Cite This Study

Olausson et al. (2021) studied this question.

synapsesocial.com/papers/69d990c92a25b240b7a3ce9dhttps://doi.org/10.1111/aas.13994
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