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September 1, 2017Biomacromolecules344 citations

Degradable Adhesives for Surgery and Tissue Engineering

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VBVrushali BhagatMBMatthew L. Becker

Key Points

  • To review the development, utility, advantages, and limitations of degradable polymeric tissue adhesives in surgery and tissue engineering.
  • Reviewed biomedical literature on various classes of degradable polymeric tissue adhesives.
  • Categorized adhesive groups according to their functional properties, biomedical indications, and clinical trade-offs.
  • Evaluated critical engineering and biological challenges facing the development of next-generation bioadhesives.
  • Cataloged distinct classes of degradable tissue adhesives along with their specific surgical utilities, benefits, and drawbacks.
  • Identified key biological and material challenges limiting current formulations, providing guidance for future biomaterial design.

Abstract

This review highlights the research on degradable polymeric tissue adhesives for surgery and tissue engineering. Included are a comprehensive listing of specific uses, advantages, and disadvantages of different adhesive groups. A critical evaluation of challenges affecting the development of next generation materials is also discussed, and insights into the outlook of the field are explored.

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Cite This Study

Bhagat et al. (2017) studied this question.

synapsesocial.com/papers/69d9d82e5e5bcb4e3b837fe3https://doi.org/10.1021/acs.biomac.7b00969
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