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February 8, 2023JAMA Cardiology64 citationsOpen Access

Association of Long-term Change in N-Terminal Pro–B-Type Natriuretic Peptide With Incident Heart Failure and Death

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XJXiaoming JiaMRMahmoud Al RifaiRHRon C. Hoogeveen

Structured PICO

Does long-term (6-year) change in NT-proBNP reflect dynamic change in risk for incident heart failure and death in community-dwelling adults without prevalent clinical HF?

P
Population
Community-dwelling adults without prevalent clinical heart failure (pre-HF)
I
Intervention
Serial NT-proBNP measurements (6-year change in NT-proBNP)
O
Outcome
Incident heart failure and deathhard clinical

Serial NT-proBNP measurements over 6 years can improve risk stratification for incident heart failure and death in adults without prevalent clinical HF.

Abstract

In this study, 6-year change in NT-proBNP reflected dynamic change in risk for HF events and death among community-dwelling adults without prevalent clinical HF. These results support the utility of serial NT-proBNP measurements to improve risk stratification of patients with pre-HF.

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Cite This Study

Jia et al. (2023) studied this question.

synapsesocial.com/papers/69d9daada1d151c65f6854f6https://doi.org/10.1001/jamacardio.2022.5309
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