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April 11, 2026European Journal of Pediatrics0 citationsOpen Access

Temporal trends and correlates of Helicobacter pylori prevalence in children undergoing upper gastrointestinal endoscopy

KIKadir IşıkBVBurcu VolkanDEDeniz Ertem

Key Points

  • This research aims to examine the trends in Helicobacter pylori prevalence among children undergoing endoscopy.
  • Longitudinal analysis over 10 years.
  • Sample included symptomatic children undergoing upper gastrointestinal endoscopy.
  • Assessment of precancerous lesions and H. pylori infection rates.
  • H. pylori prevalence decreased from 47.9% in 2010 to 23.4% in 2020.
  • The most significant decline observed in school-aged children and adolescents.
  • Precancerous lesions like gastric atrophy and intestinal metaplasia were rare.

Abstract

• We observed a nearly 50% decline in H. pylori prevalence over a 10-year period, from 47.9% in 2010 to 23.4% in 2020 among symptomatic children, with the most pronounced decline in school-aged children and adolescents. • In this cohort, precancerous lesions were uncommon (gastric atrophy 2.3%, intestinal metaplasia 1.38%) and, although H. pylori infection was nearly twofold higher in children with these lesions, they were not independently associated with H. pylori infection.

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Cite This Study

Işık et al. (2026) studied this question.

synapsesocial.com/papers/69d9e5ec78050d08c1b761fdhttps://doi.org/10.1007/s00431-026-06908-4
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