To explore the latest advancements in drug discovery targeting BACE1 for Alzheimer's treatment.
Review of recent literature on BACE1 inhibitors
Analysis of amyloid beta peptide accumulation
Evaluation of therapeutic design strategies
Identification of novel BACE1 inhibitors
Evidence of reduced amyloid beta accumulation in models
Potential therapeutic pathways to mitigate cognitive decline
Abstract
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. A key feature of AD is the accumulation of amyloid beta (Aβ) peptides in the...