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April 2, 2013Hepatology250 citationsOpen Access

Response-Guided Peginterferon Therapy in Hepatitis B E Antigen-Positive Chronic Hepatitis B Using Serum Hepatitis B Surface Antigen Levels

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MSMilan J. SonneveldBHBettina E. HansenTPTeerha Piratvisuth

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Abstract

HBsAg is a strong predictor of response to PEG-IFN in HBeAg-positive CHB. HBV genotype-specific stopping-rules may be considered at week 12, but treatment discontinuation is indicated in all patients with HBsAg >20,000 IU/mL at week 24, irrespective of HBV genotype.

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Cite This Study

Sonneveld et al. (2013) studied this question.

synapsesocial.com/papers/69da56f5b48bb130d4684bd6https://doi.org/10.1002/hep.26436
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