Does 24-hour NIHSS adjusted for baseline predict 90-day mRS outcomes better than NIHSS score change in endovascular therapy-treated patients?
Baseline-adjusted 24-hour NIHSS is a superior predictor of 90-day functional outcomes following endovascular thrombectomy compared to NIHSS score change.
Twenty-four-hour NIHSS, adjusted for baseline, was the strongest predictor of both dichotomous and ordinal 90-day mRS outcomes for endovascular therapy-treated patients. A dichotomous 24-hour NIHSS score of ≤7 was the second-best predictor. Although ΔNIHSS, continuous and dichotomized at ≥4, predicted 90-day outcomes, absolute 24-hour NIHSS definitions performed better.
Mistry et al. (2021) studied this question.