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March 5, 2012British journal of surgery547 citationsOpen Access

Meta-analysis of individual patient data to examine factors affecting growth and rupture of small abdominal aortic aneurysms

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MSMichael SweetingSTSimon G. ThompsonLBLouise Brown

Structured PICO

What factors and medications affect the growth and rupture of small abdominal aortic aneurysms?

P
Population
Individuals with a small abdominal aortic aneurysm (AAA)
I
Intervention
Cardiovascular risk reduction drugs and risk factor assessment (diabetes, smoking, sex)
O
Outcome
Growth and rupture of small abdominal aortic aneurysmshard clinical

Follow-up schedules for small AAAs should incorporate diabetes and smoking status, and a lower threshold for surgical intervention in women may be justified.

Abstract

Follow-up schedules for individuals with a small AAA may need to consider diabetes and smoking, in addition to aneurysm diameter. The differing risk factors for growth and rupture suggest that a lower threshold for surgical intervention in women may be justified. No single drug used for cardiovascular risk reduction had a major effect on the growth or rupture of small aneurysms.

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Cite This Study

Sweeting et al. (2012) studied this question.

synapsesocial.com/papers/69daa4af2d871caad68359dfhttps://doi.org/10.1002/bjs.8707
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