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August 6, 2007Hepatology404 citationsOpen Access

Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes

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SJSwati Joshi‐BarveSBShirish BarveKAKiranmayi Amancherla

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Abstract

These data demonstrate for the first time that lipid accumulation in hepatocytes can stimulate IL-8 production, thereby potentially contributing to hepatic inflammation and consequent liver injury.

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Joshi‐Barve et al. (2007) studied this question.

synapsesocial.com/papers/69daba52387cf706986877e4https://doi.org/10.1002/hep.21752
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  5. 5Palmitate Activates the NF-κB Transcription Factor and Induces IL-6 and TNFα Expression in 3T3-L1 Adipocytes2005 · 343 citations