Concurrent Chemotherapy and Radiotherapy for Organ Preservation in Advanced Laryngeal Cancer

Key Points

• This research aims to evaluate the efficacy of concurrent chemotherapy and radiotherapy for laryngeal cancer preservation.
• Conducted a randomized trial comparing concurrent cisplatin with radiotherapy to induction chemotherapy followed by radiotherapy and radiotherapy alone.
• Included patients with advanced laryngeal cancer.
• Concurrent radiotherapy with cisplatin demonstrated superior laryngeal preservation compared to induction chemotherapy followed by radiotherapy and radiotherapy alone, with significant locoregional control.