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August 16, 2016JAMA494 citationsOpen Access

Acute Aortic Dissection and Intramural Hematoma

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FMFiras F. MussaJHJoshua D. HortonRMRameen S. Moridzadeh

Structured PICO

P
Population
Patients presenting with acute chest or back pain and high blood pressure with suspected acute aortic syndrome (AAS)
I
Intervention
Diagnostic imaging (computerized tomography, magnetic resonance imaging, transesophageal echocardiography) and type-specific repair (open surgical repair for type A, thoracic endovascular aortic repair for type B)

Highlights the importance of prompt imaging diagnosis and tailored surgical or endovascular management for acute aortic syndromes.

Limitations

  • paucity of randomized trials

Abstract

Because of the high mortality rate, AAS should be considered and diagnosed promptly in patients presenting with acute chest or back pain and high blood pressure. Computerized tomography, magnetic resonance imaging, and transesophageal echocardiography are reliable tools for diagnosing AAS. Available data suggest that open surgical repair is optimal for treating type A (ascending aorta) AAS, whereas thoracic endovascular aortic repair may be optimal for treating type B (descending aorta) AAS. However, evidence is limited by the paucity of randomized trials.

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Cite This Study

Mussa et al. (2016) studied this question.

synapsesocial.com/papers/69dac4b2aae38ff6ad8368e3https://doi.org/10.1001/jama.2016.10026
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Valiant Thoracic Stent-Graft Deployed With the New Captivia Delivery System: Procedural and 30-Day Results of the Valiant Captivia Registry2012 · 45 citations
  2. 2Thoracic aortic dissection: diagnosis with transesophageal echocardiography versus MR imaging.1995 · 70 citations
  3. 3Outcomes of medically treated patients with aortic intramural hematoma2002 · 122 citations
  4. 4Acute Aortic Dissection: Perspectives from the International Registry of Acute Aortic Dissection (IRAD)2008 · 455 citations