Does variable-loop circular PFA compare favorably to fixed-loop circular PFA for acute outcomes in AF ablation?
Variable-loop circular PFA catheters demonstrate high acute efficacy, favorable safety, and versatility for non-pulmonary vein ablation compared to fixed-loop systems.
This first clinical comparison demonstrated high acute efficacy and favorable safety profiles, with notable procedural differences reflecting their distinct workflows of 2 circular PFA catheter systems for AF ablation. Likewise, this includes the first reported successful CTI, SVC and mitral isthmus ablation using VLCC reflecting its versatility for ablation. Further research is warranted to assess long-term outcomes and lesion durability.
Yogarajah et al. (2025) studied this question.