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April 12, 2026JACC Case Reports0 citationsOpen Access

Unprecedented Complication of Left Bundle Branch Pacing

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DKDilip KumarSKSrashti KulshresthaRCRabin Chakraborty

Key Result

Left bundle branch pacing can cause rare mechanical complications like septal injury and mitral chordal entrapment, which may be prevented by monitoring impedance changes during lead manipulation.

Key Points

  • The aim is to explore the rare complications associated with conduction system pacing, specifically focusing on mechanical issues.
  • Observation of pacing parameters during lead manipulation.
  • Assessment of impedance changes to identify potential complications.
  • Monitoring resistance during procedures to detect tissue entrapment.
  • Identified mechanical complications such as septal injury and mitral chordal entrapment.
  • Demonstrated that abrupt changes in impedance can indicate possible structural damage.
  • Highlighting the importance of monitoring pacing parameters for early recognition of complications.

Structured PICO

P
Population
Patients undergoing conduction system pacing (left bundle branch pacing)
I
Intervention
Left bundle branch pacing
O
Outcome
Mechanical complications (septal injury and mitral chordal entrapment)safety

Monitoring pacing parameters such as abrupt impedance changes or resistance during lead manipulation may aid in early recognition of tissue entrapment and prevent structural damage during left bundle branch pacing.

Abstract

Although rare, conduction system pacing can result in mechanical complications such as septal injury and mitral chordal entrapment. Monitoring of pacing parameters, including abrupt impedance changes or resistance during lead manipulation, may aid in early recognition of tissue entrapment and prevent structural damage.

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Cite This Study

Kumar et al. (2026) studied this question. Left bundle branch pacing can cause rare mechanical complications like septal injury and mitral chordal entrapment, which may be prevented by monitoring impedance changes during lead manipulation.

synapsesocial.com/papers/69db361c4fe01fead37c4603https://doi.org/10.1016/j.jaccas.2026.107858
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