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April 12, 20260 citationsOpen Access

Comparison of SIGN interlocking nailing and compression plating in the treatment of aseptic non-union of femoral shaft fractures

MAMike T. AchorRERichard C. Echem

Key Points

  • To compare the effectiveness of SIGN interlocking nailing versus compression plating in treating aseptic non-union of femoral shaft fractures.
  • Prospective cohort study over 31 months
  • Patients recruited from University of Port Harcourt Teaching Hospital
  • Random assignment into two groups for treatment
  • Group A underwent SIGN interlocking nailing
  • Group B underwent compression plating with osteosynthesis
  • Forty out of 42 patients completed the study
  • Union rate for SIGN interlocking nailing was 80%
  • Union rate for compression plating was 95%
  • No statistically significant difference in outcomes (p=0.342)
  • Variables like blood loss and healing duration were comparable

Abstract

Background: Aseptic non-union of the shaft of femur presents a treatment challenge with the need for prolonged hospitalization, multiple procedures and economic burden. The choice of treatment is influenced by facilities available in a specified centre. Aim: To compare the results of SIGN interlocking nailing and compression plating in the treatment of aseptic non-union of femoral shaft fractures. Methods: Prospective cohort study conducted over a period of thirty-one (31) months (August 2015 to March 2018). Patients with aseptic non-union of femoral shaft fractures who presented to orthopaedic units of University of Port Harcourt Teaching Hospital, Port Harcourt over the study period were recruited into the study. They were randomly grouped into two—A and B. Group A had open reduction and internal fixation with SIGN interlocking nail, while group B had their fractures fixed by compressive plate osteosynthesis. The patients were followed up for at least six months and the results compared. Results: Forty out of 42 patients completed the study. The SIGN interlocking nailing group had a union rate of 80% (n=16) in six months, while the compression plating group had 95% (n=19). The observed difference was not statistically significant (p=0.342). The two groups also had statistically comparable intra-operative blood loss, wound infection rates, duration for wound healing, post-operative limb shortening and duration of post-operative hospital stay. Conclusion: SIGN interlocking nailing and compression plating are effective methods of treatment of aseptic non-union of femoral shaft fractures. They are comparable with respect to variables evaluated in this study.

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Cite This Study

Achor et al. (2026) studied this question.

synapsesocial.com/papers/69db37254fe01fead37c514chttps://doi.org/10.60787/phmj.v20i1.252
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A PROSPECTIVE COMPARATIVE STUDY OF FUNCTIONAL OUTCOME IN PATIENTS TREATED WITH INTERLOCKING NAILING AND DYNAMIC COMPRESSION PLATING FOR FRACTURE SHAFT OF HUMERUS IN ADULTS2023
  2. 2Comparative study on femoral shaft fracture treated by plate and screws versus intramedullary interlocking nails. A clinical study2025
  3. 3A Comparative Analysis of Locking Plate versus Intramedullary Nail for Humerus Shaft Fractures2024
  4. 4Frequency of Union in Intramedullary Solid Nailing (SIGN nailing) Via Open Reduction for the Treatment of Fracture Shaft of Tibia2023
  5. 5Outcome of Locked Reamed Intramedullary Nail v/s K-NAIL Plus Augmented Plating in Aseptic Distal Femur Non-Union2024