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April 12, 2026Intelligence & Cognitive Abilities1 citationsOpen Access

Polygenicity and GxE Interactions Do Not Imply Biological Arbitrariness: Response to Commentaries by Deary et al. and Matzel & Sauce

JGJ. Jay GargusRHRichard Haier

Key Points

  • This response addresses commentaries on the role of polygenicity and gene-environment interactions in human intelligence.
  • Engaged with commentaries discussing complexities of intelligence research.
  • Highlighted advances in genetic technologies and neuroscience.
  • Emphasized the potential to tackle challenges rather than viewing them as deterring factors.
  • Reaffirmed that polygenicity and gene-environment interactions do not undermine biological aspects of intelligence.
  • Advocated for continued research in intelligence through new technologies and methods.

Abstract

We respond to two commentaries about our recent paper on molecular biology and human intelligence. They rightly point out the complexities involved, especially from polygenicity and gene X environmental interactions. Our view is that these factors do not negate an underlying biology of intelligence that can be accessible by advances in genetic and neuroscience technologies and analytic methods. We see the complexities as inspiring challenges that can be addressed rather than permanent roadblocks that discourage research.

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Cite This Study

Gargus et al. (2026) studied this question.

synapsesocial.com/papers/69db37404fe01fead37c5336https://doi.org/10.65550/001c.159544
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