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April 12, 2026JAMA Network Open0 citationsOpen Access

Risk Prediction Model for Taxane-Induced Peripheral Neuropathy in Early-Stage Cancer

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MTMeghna TrivediJUJoseph M. UngerNHN. Lynn Henry

Key Points

  • The aim is to develop a risk prediction model for taxane-induced peripheral neuropathy (TIPN) in patients with early-stage cancer.
  • Cohort study design involving participants with early-stage cancer
  • Assessment of baseline risk factors associated with TIPN
  • Development of a risk prediction model based on identified factors
  • Identification of significant baseline risk factors for TIPN
  • Creation of a predictive model to estimate TIPN risk
  • Potential for guiding treatment decisions and monitoring symptoms

Abstract

In this cohort study of participants with early-stage cancer receiving a taxane regimen, a set of baseline risk factors stratified TIPN risk. A risk prediction model may guide treatment decision-making, symptom monitoring, and enrollment in interventional trials for TIPN prevention and treatment.

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Cite This Study

Trivedi et al. (2026) studied this question.

synapsesocial.com/papers/69db383b4fe01fead37c675dhttps://doi.org/10.1001/jamanetworkopen.2026.4901
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