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June 7, 2019SHILAP Revista de lepidopterología44 citationsOpen Access

Depletion of activated macrophages with a folate receptor-beta-specific antibody improves symptoms in mouse models of rheumatoid arthritis

YHYingwen HuBWBingbing WangJSJiayin Shen

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Abstract

These data suggest that specific elimination of FR-β-expressing macrophages may constitute a highly specific therapy for multiple autoimmune and inflammatory diseases and that a recently developed human anti-human FR-β monoclonal antibody (m909) might contribute to suppression of this subpopulation of macrophages.

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Hu et al. (2019) studied this question.

synapsesocial.com/papers/69dbf47c40b636d1dda3c6ffhttps://doi.org/10.1186/s13075-019-1912-0
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