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June 20, 2019Journal for ImmunoTherapy of Cancer90 citationsOpen Access

Efficient identification of neoantigen-specific T-cell responses in advanced human ovarian cancer

SLSong LiuJMJunko MatsuzakiLWLei Wei

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Abstract

Our study demonstrated the feasibility of efficiently identifying both CD4+ and CD8+ neoantigen-specific T-cells in EOC. Autologous lymphocytes genetically engineered with tumor antigen-specific TCR can be used to generate cells for use in the personalized adoptive T-cell transfer immunotherapy.

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Cite This Study

Liu et al. (2019) studied this question.

synapsesocial.com/papers/69dc06e7ba9f92abb12a6517https://doi.org/10.1186/s40425-019-0629-6
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