Does Blood Urea Nitrogen (BUN) variation during hospitalization predict prognosis in patients with heart failure?
Elevated BUN levels on admission and discharge, or worsening BUN during hospitalization, predict worse prognosis in heart failure patients.
The BUN both on admission and on discharge is a prognostic predictor in patients with HF; however, patients with elevated levels both on admission and on discharge have the worst prognosis. Moreover, worsening or lack of improvement in BUN during hospitalization is a worse prognostic predictor. To the best of our knowledge, this is the first trial to discuss the BUN change during hospitalization in HF.
Khoury et al. (2019) studied this question.