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November 25, 2020Journal of Hepatology379 citationsOpen Access

Non-invasive stratification of hepatocellular carcinoma risk in non-alcoholic fatty liver using polygenic risk scores

CBCristiana BiancoFondazione IRCCS Ca' Granda Ospedale Maggiore PoliclinicoOJOveis JamialahmadiKarolinska InstitutetSPSerena PelusiFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

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Abstract

By analyzing variations in genes that contribute to fatty liver disease, we developed two risk scores to help predict liver cancer in individuals with obesity-related metabolic complications. These risk scores can be easily tested in the clinic. We showed that the risk scores helped to identify the risk of liver cancer both in high-risk individuals and in the general population.

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Cite This Study

Bianco et al. (2020) studied this question.

synapsesocial.com/papers/69dc925189c4deb67d3592b5https://doi.org/10.1016/j.jhep.2020.11.024
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