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September 30, 2020Biomedicine & Pharmacotherapy89 citationsOpen Access

Pomegranate flower extract bidirectionally regulates the proliferation, differentiation and apoptosis of 3T3-L1 cells through regulation of PPARγ expression mediated by PI3K-AKT signaling pathway

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TLTong LiLZLing ZhangJCJin Chen

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Abstract

PFE has a concentration-related bidirectional effect on the proliferation, differentiation and apoptosis of 3T3-L1 preadipocytes, which depends on the regulation of PI3K-Akt pathway, which is of guiding role for PFE in the treatment of type 2 diabetes, hyperlipidemia, obesity and other diseases.

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Cite This Study

Li et al. (2020) studied this question.

synapsesocial.com/papers/69dcc8c8f3d3790cb7133c82https://doi.org/10.1016/j.biopha.2020.110769
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