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November 16, 2010HypertensionOpen Access

Nighttime BP was a stronger predictor than daytime BP; night-to-day BP ratio and dipping status remained significant predictors but added little prognostic value over and beyond the 24-hour BP level.

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Why the study?

Does nighttime blood pressure predict total mortality or cardiovascular endpoints better than daytime blood pressure in hypertensive patients and general populations?

Population

Hypertensive patients (n = 23,856) and individuals randomly recruited from populations (n = 9,641)

Comparison

Nighttime blood pressure level and circadian… vs Daytime blood pressure and 24-hour blood pressure

Design

Meta-analysis

Authors

THTine W. HansenYLYan LiJBJosé Boggia

Discussion

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Overview

Nighttime BP may refine CV risk stratification beyond daytime measures; confirms superiority but leaves added value of dipping open.

Structured PICO

Does nighttime blood pressure predict total mortality or cardiovascular endpoints better than daytime blood pressure in hypertensive patients and general populations?

P
Population
Hypertensive patients (n = 23,856) and individuals randomly recruited from populations (n = 9,641)
I
Intervention
Nighttime blood pressure level and circadian profile of systolic BP assessed by ambulatory monitoring
C
Comparator
Daytime blood pressure and 24-hour blood pressure
O
Outcome
Total mortality or a composite cardiovascular end pointcomposite

Nighttime blood pressure is a stronger predictor of mortality and cardiovascular events than daytime blood pressure, suggesting ambulatory BP monitoring guidelines should be updated.

Cite This Study

Hansen et al. (2010) studied this question.

synapsesocial.com/papers/69dcc969a5c75be4cfe547d9https://doi.org/10.1161/hypertensionaha.109.133900
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