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January 1, 2019Open Medicine16 citationsOpen Access

Effects of dexmedetomidine on the RhoA /ROCK/ Nox4 signaling pathway in renal fibrosis of diabetic rats

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JCJihua ChenCCChen CaiBXBao Xubin

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Abstract

Dex is possible to inhibit the expression of α-SMA and renal fibrous substance deposition in rat kidney via RhoA/ROCK/Nox4 signaling pathway, thereby reducing early kidney damage in model rats.

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Chen et al. (2019) studied this question.

synapsesocial.com/papers/69dcca31c099bcfdbb133b16https://doi.org/10.1515/med-2019-0105
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