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July 6, 2017BMC Cancer28 citationsOpen Access

ALK-rearranged lung squamous cell carcinoma responding to alectinib: a case report and review of the literature

NMNobuaki MamesayaKNKazuhisa NakashimaTNTateaki Naito

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Abstract

To the best of our knowledge, this is the first case report to discuss the successful management of ALK-rearranged lung SqCC with alectinib. We propose that molecular testing for driver mutations should be considered in young patients with a light or no smoking history, even if the histological findings correspond with SqCC, and alectinib therapy represents a reasonable option in cases of ALK-rearranged lung SqCC.

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Mamesaya et al. (2017) studied this question.

synapsesocial.com/papers/69dcca810de68e8319e5382fhttps://doi.org/10.1186/s12885-017-3468-1
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