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January 21, 2017Intensive Care Medicine907 citationsOpen Access

Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial

MMMelanie MeerschCSC. G. SchmidtAHA. Hoffmeier

Structured PICO

Does the implementation of KDIGO guidelines reduce the frequency and severity of AKI in biomarker-identified high-risk patients undergoing cardiac surgery?

P
Population
High risk patients identified by biomarkers undergoing cardiac surgery
I
Intervention
Implementation of the KDIGO guidelines
C
Comparator
Standard care
O
Outcome
Frequency and severity of acute kidney injury (AKI)hard clinical

Implementing KDIGO guidelines in biomarker-identified high-risk patients reduces the frequency and severity of AKI after cardiac surgery.

Limitations

  • Not adequately powered to examine mortality and long-term renal outcomes
  • Likely single-center (multicenter trials warranted)

Abstract

An implementation of the KDIGO guidelines compared with standard care reduced the frequency and severity of AKI after cardiac surgery in high risk patients. Adequately powered multicenter trials are warranted to examine mortality and long-term renal outcomes.

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Cite This Study

Meersch et al. (2017) studied this question.

synapsesocial.com/papers/69dd198aa6f240e91f1336e1https://doi.org/10.1007/s00134-016-4670-3
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