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December 16, 2005Clinical Infectious Diseases263 citationsOpen Access

Human Parechovirus Infections in Dutch Children and the Association between Serotype and Disease Severity

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KBKimberley BenschopJSJanke SchinkelRMR. P. Minnaar

Structured PICO

Is HPeV3 infection associated with increased disease severity, such as sepsis-like illness and central nervous system involvement, in neonates?

P
Population
Dutch young children and neonates with Human Parechovirus (HPeV) infections during the period of 2000-2005
I
Intervention
HPeV3 infection (exposure)
C
Comparator
Other HPeV serotypes
O
Outcome
Sepsis-like illness and central nervous system involvement

HPeV3 infection is associated with severe clinical presentations, including sepsis-like illness and central nervous system involvement, in neonates.

Abstract

We report HPeV infections in young children during the period of 2000-2005 and show an association between HPeV3 infection and sepsis-like illness and central nervous system involvement in neonates.

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Cite This Study

Benschop et al. (2005) studied this question.

synapsesocial.com/papers/69dd1afc0219ae88a9e52dc5https://doi.org/10.1086/498905
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