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September 30, 2019New England Journal of Medicine1,495 citationsOpen Access

Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer

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SKScott KopetzAGAxel GrotheyRYRona Yaeger

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Abstract

A combination of encorafenib, cetuximab, and binimetinib resulted in significantly longer overall survival and a higher response rate than standard therapy in patients with metastatic colorectal cancer with the BRAF V600E mutation. (Funded by Array BioPharma and others; BEACON CRC ClinicalTrials.gov number, NCT02928224; EudraCT number, 2015-005805-35.).

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Kopetz et al. (2019) studied this question.

synapsesocial.com/papers/69dd1c4a7a4feaa6eae52e26https://doi.org/10.1056/nejmoa1908075
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