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November 14, 2010Circulation Arrhythmia and Electrophysiology169 citationsOpen Access

Antiarrhythmics After Ablation of Atrial Fibrillation (5A Study)

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PLPeter Leong‐SitElectrophysiologyJRJean-François RouxElectrophysiologyEZErica S. ZadoElectrophysiology

Structured PICO

Does short-term use of AADs after AF ablation prevent arrhythmia recurrence at 6 months?

P
Population
Patients after ablation of atrial fibrillation
I
Intervention
Short-term early use of antiarrhythmic drugs (AADs)
C
Comparator
No early AADs (off AADs)
O
Outcome
Arrhythmia recurrence at 6 months

Short-term AAD use post-AF ablation reduces early arrhythmias but does not improve 6-month recurrence rates.

Abstract

Although short-term use of AADs after AF ablation decreases early recurrence of atrial arrhythmias, early use of AADs does not prevent arrhythmia recurrence at 6 months. Early AF recurrence on or off AADs during the initial 6-week blanking period is a strong independent predictor of long-term AF recurrence.

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Cite This Study

Leong‐Sit et al. (2010) studied this question.

synapsesocial.com/papers/69dd4e825ea84e5556101343https://doi.org/10.1161/circep.110.955393
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