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January 2, 2025Diabetes Care33 citationsOpen Access

Tirzepatide Associated With Reduced Albuminuria in Participants With Type 2 Diabetes: Pooled Post Hoc Analysis From the Randomized Active- and Placebo-Controlled SURPASS-1–5 Clinical Trials

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EAEllen M. ApperlooKTKatherine R. TuttleIPImre Pávó

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Abstract

In this post hoc analysis in people with type 2 diabetes, including those with chronic kidney disease, tirzepatide was associated with a clinically relevant decreased UACR versus comparators, suggesting a potential kidney-protective effect.

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Apperloo et al. (2025) studied this question.

synapsesocial.com/papers/69dd513080eea7d3f699b458https://doi.org/10.2337/dc24-1773
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