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November 3, 2011American Journal of Hypertension68 citationsOpen Access

The Dietary Phase 2 Protein Inducer Sulforaphane Can Normalize the Kidney Epigenome and Improve Blood Pressure in Hypertensive Rats

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GSGamarallage Vijitha Kumara SenanayakeABAli BanigeshLWLingyun Wu

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Abstract

Sulforaphane administration rectified pathological abnormalities in SHRSP kidneys and significantly improved blood pressure. This was associated with normalization of global kidney DNA methylation suggesting that DNA methylation could be associated with hypertension.

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Senanayake et al. (2011) studied this question.

synapsesocial.com/papers/69dd543f80eea7d3f699b793https://doi.org/10.1038/ajh.2011.200
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