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January 1, 1999Physics in Medicine and Biology112 citations

Developments in component-based normalization for 3D PET

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RBRamsey D. BadawiPMPaul Marsden

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Abstract

Normalization in positron emission tomography (PET) is the process of ensuring that all lines of response joining detectors in coincidence have the same effective sensitivity. In three-dimensional (3D) PET, normalization is complicated by the presence of a large proportion of scattered coincidences, and by the fact that cameras operating in 3D mode encounter a very wide range of count-rates. In this work a component-based normalization model is presented which separates the normalization of true and scattered coincidences and accounts for variations in normalization effects with count-rate. The effects of the individual components in the model on reconstructed images are investigated, and it is shown that only a subset of these components has a significant effect on reconstructed image quality.

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Badawi et al. (1999) studied this question.

synapsesocial.com/papers/69dd5f5d0a7b4bc8c4101c7dhttps://doi.org/10.1088/0031-9155/44/2/020
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