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June 10, 2022Journal of Neuroinflammation240 citationsOpen Access

Activating cGAS–STING axis contributes to neuroinflammation in CVST mouse model and induces inflammasome activation and microglia pyroptosis

RDRui DingHLHaiyan LiYLYaqi Liu

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Abstract

Our data demonstrate that repression of the cGAS-STING pathway diminishes the neuroinflammatory burden of CVST and highlight this approach as a potential therapeutic tactic in CVST-mediated pathologies.

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Ding et al. (2022) studied this question.

synapsesocial.com/papers/69dd60060a7b4bc8c4101cd0https://doi.org/10.1186/s12974-022-02511-0
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