Does catheter ablation reduce all-cause mortality compared to medical therapy in patients with atrial fibrillation?
Catheter ablation provides mortality and hospitalization benefits over medical therapy in patients with atrial fibrillation, particularly those with concurrent heart failure with reduced ejection fraction.
CA is associated with all-cause mortality benefit, that is driven by patients with AF and heart failure with reduced ejection fraction. CA reduces cardiovascular hospitalizations and recurrences of atrial arrhythmia for patients with AF. Younger patients and men appear to derive more benefit from CA.
Asad et al. (2019) studied this question.